In most cases where the the politicians debate about policy they can usually cite a bevy of economic experts, academic papers, and think-tank research to bolster their respective positions, but there are some issues where the experts pretty much all agree and the politicians don’t want to hear it.
One fun example is the tax plan NPR asked 5 economists to create that–though it reflects pretty unanimous economic consensus–is a political non-starter with either the Democrats or the Republicans. (Hint: removing the mortgage interest tax deduction doesn’t make anyone happy.)
Another example that’s like that is price gouging.